One Year Anniversary of the Tox Blog
By Loza Taye | August 22nd, 2024
“We aim to promote better science and support the transition towards more humane and effective methods by covering legislative developments, innovative research techniques, and legal considerations…”
Is Raising Genetically Modified Pigs A Way to Solve the Organ Transplant Shortage?
By Breanne Kincaid and Rebecca Critser | August 8th, 2024
“Given the public health risks, welfare concerns, and relative ease with which human organ procurement solutions can be implemented, is a multi-billion dollar investment in the research and infrastructure required to make gene-edited pig organs necessary or appropriate?”
Meeting the Requirements of the AWA Workshop Recap
By Loza Taye | July 25th, 2024
“...AWIC hosted a workshop to promote successful research planning that meets the AWA requirements. Key takeaways from this event included the importance of early planning, cost considerations, effective search strategies, cultivating empathy, embracing progress, and enhancing proficiency in alternatives research.”
MPS World Summit 2024 Recap
By Breanne Kincaid & Yiguang Zhu | July 11th, 2024
“In attending the MPS World Summit and other conferences and webinars, it is increasingly clear that MPS developers and end-users would all benefit from clearly enumerated regulatory requirements describing what benchmarks must be met in order for MPS data to be accepted for particular use contexts.”
Professional Perspectives: ALR Special Edition
By Lenore Montanaro | June 26th 2024
“Finding the best way forward will take dedication, effort, and cooperation among the scientific community and animal advocates.”
ICCVAM 2024 Public Forum Highlights
By Loza Taye | June 13th, 2024
“The 2024 ICCVAM Public Forum highlighted progress and future directions in alternative testing methods and how that work is proceeding in federal agencies and some partners. The presentations and discussions underscored a shared commitment to reducing animal testing while improving regulatory science and maintaining rigorous safety standards.”
Revolutionizing Healthcare: How Induced Pluripotent Stem Cells are Paving the Way for Personalized Medicine
By Zachary Liebowitz | May 30th, 2024
“Not only is this model of personalized medicine more clinically relevant than today’s approaches, it is simultaneously more humane, time effective, and cost efficient.”
Innovation in New Approach Methodologies at the 2024 Society of Toxicology Meeting
By Breanne Kincaid | May 16th, 2024
“By harnessing the power of technology, fostering collaboration, and prioritizing regulatory acceptance, we can chart a course towards a safer, more sustainable future.”
Briefing Over Breakfast
By Andrew Obeng | May 9th, 2024
“Earlier this week, Dr. Paul Locke and Rebecca Critser as well as White Coat Waste Project’s Justin Goodman presented their comments on the reversal of the EPA’s promises to minimize animal testing by 2035”
Innovative Solutions for an Invisible Threat: Enhancing PFAS Assessment
By Loza Taye | May 2nd, 2024
“The PFAS public health threat demands rapid and sustained action and innovative solutions. Increasing evidence indicates that NAMs should be prioritized as a path to tackle the sizeable chemical class with speed and efficacy.”
Animal Experimentation Regulations in Japan and Recommended Legal Education
By Kenta Minamitani | April 18th, 2024
“Enhancing the understanding and application of animal law, guided by ethical imperatives and sustainable scientific practices, can not only significantly enrich legal education in Japan, but also improve the circumstances regarding animal testing generally.”
Virtual Testimony Before the Maryland Legislature to Support Senate Bill 761
By Sherman McFarland | April 4th, 2024
[Senate Bill 761] represents a humane step forward for animals in Maryland—in particular, cats and dogs—and I hope that it becomes available for reconsideration soon.
A Day at the Capitol: Cruelty Free Science Day
By Andrew Obeng | March 21st, 2024
“On March 7th, our Toxicology Policy team leader, Dr. Paul Locke, Hopkins doctoral student Breanne Kincaid, and post-doctoral student Itzy Erin Morales Pantoja, presented their research at a Capitol Hill briefing hosted by Cruelty Free International.”
Your Body, Your Treatment: The Clinical Potential of Microphysiological Systems in Personalized Medicine
By Loza Taye | March 7th, 2024
“Despite challenges, MPS are a promising platform in personalized medicine. MPS enhance research capabilities within disease modeling, drug testing, and regenerative medicine. As the technology advances, it offers unprecedented insights into disease progression and customized treatment strategies.”
The American Bar Association joins the fight to promote better science
By Paul Locke | February 22nd, 2024
In passing this resolution, the ABA has recognized the importance that replacement alternatives are playing now and will play in the future.
Three State Bills/Laws That Don’t Go Far Enough To Reduce And Replace Animals Used In Testing (Part 2)
By Sherman McFarland | February 7th, 2024
The medical research exemptions in California’s law, Illinois’ law, and Massachusetts’ bill are so broad that these pieces of legislation have been rendered almost completely ineffective.
NAMs and MPS and Organoids, Oh My!
By Breanne Kincaid | January 24th, 2024
The field of in vitro toxicology is moving forward rapidly, and there are numerous novel technologies now available that are poised to advance the physiological relevance of toxicity testing for human risk and hazard assessment.
Could Octopuses Become the Next “Lab Rat”?
By Daria Bednarczyk | January 11th, 2024
As the common English saying goes, “just because you can doesn’t mean you should.” This declaration significantly ties into the topic of using animals for laboratory experimentation…
Reimagining Legacy Animal Data Through the Lens of AI
By Yiguang Zhu | December 14, 2023
This August, members of our team attended the 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC-12), a significant event dedicated to advancing the 3Rs principles (replacement, reduction, and refinement) in scientific research, industry, and regulatory practices…
Where Do New Approach Methodologies Belong in Toxicity Testing? Key Takeaways from ASCCT
By Breanne Kincaid | November 9, 2023
With over 350,000 discrete chemical compounds and mixtures in commerce globally – many of which have never been thoroughly assessed for their risk to human health – it is imperative that industries and regulators have access to fast, accurate, human-relevant toxicity testing methods…