• We are a group of scientists and lawyers committed to improving public health and welfare by bringing cutting-edge knowledge to regulatory decision-making.

  • The JHU Toxicology Policy team advances alternatives to animals in the biomedical sciences and toxicity testing through evidence-based advocacy, research, and collaboration.

  • To bring 21st century science into regulatory decision-making.

A non-partisan team bringing 21st century science into regulatory decision making. Better outcomes, fewer animals, stronger public health.

  • Close-up of a medical ventilator or anesthesia machine panel with circular openings.

    Research Articles

    Take a look at published research articles written by our team members.

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    News Articles

    Notable headlines and public appearances made by the team.

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  • Close-up of a Medicare Part B prescription drug plan summary showing the medication name, coverage details, and monthly drug cost of $63.

    Videos and Interviews

    Recordings and interviews featuring team members.

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    Tox Blog

    Blog posts made by both team members and students discussing toxicology related topics.

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Latest Blog Posts

Tox Blog
Transitioning to Human-Centered Science:  An Off-Ramp and Transition Plan
Transitioning to Human-Centered Science:  An Off-Ramp and Transition Plan

By Paul Locke | September 4th, 2025

“For those of us who have been advocating for the development, use and adoption of human centered NAMs, the Roadmap and these announcements are a breath of fresh air. It seems that – finally – the federal government has turned the corner. But talking the talk is not enough. The transition to human centered science and away from animal testing needs an implementation plan …”

Image by Chokniti Khongchum

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Professional Perspectives: Wisconsin Court Orders Criminal Investigation of Beagle Breeder Ridglan Farms
Professional Perspectives: Wisconsin Court Orders Criminal Investigation of Beagle Breeder Ridglan Farms

By Conley Wouters | August 21st, 2025

“Regardless of the outcome of the investigation, Judge Lanford’s opinion highlights evidence of decades of egregious cruelty and immense animal suffering at Ridglan Farms. That alone might catalyze a renewed push for change from those who are working to protect—and eventually replace—animals used in research.”

Image by azerbaijan_stockers

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From Option to Obligation: The Legal Imperative for NAMs
From Option to Obligation: The Legal Imperative for NAMs

By Jo Anderson | August 7th, 2025

“Regulatory agencies must move from encouraging NAMs to requiring them where scientifically justified. Once merely regarded as alternatives to animal testing, NAMs have now emerged as a driving force in regulatory science.”

Image by NIH

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A Bright Tomorrow for Therapeutic Orphans: The Potential for New Approach Methodologies to Bridge Data Gaps for Pregnant Patients
A Bright Tomorrow for Therapeutic Orphans: The Potential for New Approach Methodologies to Bridge Data Gaps for Pregnant Patients

By Matthew Durthaler | July 24th, 2025

“As caution often precludes pregnant humans from serving as models of their own physiology, various non-human animal models have been employed. While these models have displayed some value, they are severely limited by interspecies variation and thus serve as subpar predictors of gravid human physiology.”

Sonogram captured by Matthew Durthaler, used with permission

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Our Tiny Allies in Toxicological Testing Part 2 – Transparent Roundworms as Alternative Models 
Our Tiny Allies in Toxicological Testing Part 2 – Transparent Roundworms as Alternative Models 

By Aaradhya Diwan | July 10th, 2025

“There are numerous opportunities for using C. elegans as a model for toxicity testing, thanks to their unique advantages and translational relevance to human health, as demonstrated in applications to neuroscience and developmental biology.”

Image by Zeynep F. Altun

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Unveiling IACUC members: Triumph for rule of law and animal welfare or a dangerous precedent? A closer look at P. Poe 5 et al. v University of Washington et al.
Unveiling IACUC members: Triumph for rule of law and animal welfare or a dangerous precedent? A closer look at P. Poe 5 et al. v University of Washington et al.

By Akosua Dufie and Jo Anderson | June 26th, 2025

“While privacy and transparency appear to be contradictory in this instance, their practical implementation are not mutually exclusive. With a careful balancing strategy, both needs can be accommodated and satisfied.”

Image by Pexels

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Meet the Team

We are a group of scientists and lawyers committed to improving public health and welfare by bringing cutting-edge knowledge to regulatory decision-making.

Upcoming Events

Events
Reviewing The Use Of Two Species In Toxicity Testing For Human Pharmaceuticals
Oct 24
Reviewing The Use Of Two Species In Toxicity Testing For Human Pharmaceuticals

Help shape the future of toxicity testing

Andrea Uhlig at SOT2022
Screenshot of a virtual meeting with six diverse participants, five women and one man, in different indoor settings, smiling and looking at the camera.
Team Lunch at Alexander's Tavern
A man standing at a podium with the United States Senate emblem, giving a presentation. A woman is seated at a table to his left, looking up at him. There is an American flag and a large carved emblem of the U.S. eagle on the wall behind them.
Group of nine people standing indoors, all wearing face masks, in front of an American flag and a government emblem.
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Group of 12 diverse professionals at a conference or meeting, smiling, indoors with warm lighting and a modern decor background.
A group of people standing in front of the University of Silesia building, posing for a photo.
Four individuals standing in front of a backdrop with 'Animal Legal Defense Fund' logos, two women holding awards, at an event
Group of seven people standing in front of a backdrop with the logo of the Animal Legal Defense Fund, smiling, with two holding awards.
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Group of six people standing in front of a RADON REDUCTION ACTIVISM banner holding a sign that reads 'Lung Cancer Awareness'.

To Encourage Progress in Alternatives-to-Animal Testing We Must:

Increase Transparency and Innovation in Public Health

Advocate for Human Centric Technologies to Replace Animal Tests